Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2073495 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1 | |
| SCHEMBL14967980 | 0.79 | — | — | |
| SCHEMBL799514 | 0.74 | GAA (0.34) | — | |
| SCHEMBL1184698 | 0.74 | GAA (0.34) | — | |
| SCHEMBL1183666 | 0.74 | GAA (0.34) | — | |
| SCHEMBL9801567 | 0.72 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL3429440 | 0.69 | MAPK1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL3428847 | 0.69 | MAPK1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL14438561 | 0.69 | MAPK1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL14967981 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780026-A2 | HCV NS3 PROTEASE INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013074386-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |