SCHEMBL14968007

SCHEMBL14968007

COc1ccc(C2OC2(C(=O)OC2CC2)c2ccc(OC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
SLC6A2 P23975 1/20 0.39
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
OPRK1 P41145 1/20 0.38
GAA P10253 2/20 0.37
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 4/20 0.36
HTT P42858 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TSHR P16473 1/20 0.36
RECQL P46063 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16109833 0.95 MEN1 (0.43) MEN1KMT2ASLC6A4SLC6A3SLC6A2
SCHEMBL14967820 0.95 MEN1 (0.40) MEN1KMT2ASLC6A4SLC6A3SLC6A2
SCHEMBL16108674 0.95 SLC6A4 (0.41) MEN1KMT2ASLC6A4SLC6A3SLC6A2
SCHEMBL16108687 0.94 TP53 (0.40) MEN1KMT2ASLC6A4SLC6A3RAB9A
SCHEMBL16108956 0.94 TSHR (0.41) MEN1KMT2ASLC6A4SLC6A3SLC6A2
SCHEMBL16108684 0.91 KMT2A (0.40) MEN1KMT2ASLC6A4SLC6A3ALDH1A1
SCHEMBL16109939 0.91 KMT2A (0.40) MEN1KMT2ASLC6A4SLC6A3SLC6A2
SCHEMBL16109854 0.90 TP53 (0.40) MEN1KMT2ASLC6A4SLC6A3RAB9A
SCHEMBL16109899 0.89 TSHR (0.40) MEN1KMT2ASLC6A4SLC6A3ATM
SCHEMBL16110003 0.89 TSHR (0.40) MEN1KMT2ASLC6A4SLC6A3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed