SCHEMBL14968189

SCHEMBL14968189

COc1ccc(C2(C(=O)OC3CCCCC3)OC23CCC3)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NPC1 O15118 4/20 0.40
RAB9A P51151 4/20 0.40
EPHX1 P07099 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ATM Q13315 1/20 0.38
SLC6A4 P31645 3/20 0.37
SLC6A3 Q01959 3/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967068 0.99 MEN1 (0.40) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14968224 0.98 EPHX2 (0.41) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14969480 0.98 EPHX2 (0.41) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14968280 0.98 EPHX2 (0.41) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14968283 0.96 SLC6A4 (0.40) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14968171 0.96 ATM (0.39) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14969479 0.95 SLC6A4 (0.40) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14967965 0.95 MEN1 (0.41) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14966972 0.94 SLC6A4 (0.41) EPHX2MEN1KMT2ANPC1RAB9A
SCHEMBL14967352 0.94 CYP3A4 (0.40) EPHX2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed