Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9114040 | 0.82 | CA1 (0.40) | CA1CA9 | |
| SCHEMBL14952902 | 0.81 | CA1 (0.30) | CA1CA9 | |
| SCHEMBL14953054 | 0.81 | CA1 (0.30) | CA1CA9 | |
| SCHEMBL14966060 | 0.81 | CA1 (0.30) | CA1CA9 | |
| SCHEMBL5585129 | 0.80 | CA1 (0.41) | CA1CA9 | |
| SCHEMBL22921248 | 0.80 | CA1 (0.41) | CA1CA9 | |
| SCHEMBL1107367 | 0.72 | — | — | |
| SCHEMBL14131228 | 0.72 | — | — | |
| SCHEMBL14131263 | 0.72 | — | — | |
| SCHEMBL28481690 | 0.70 | CA1 (0.37) | CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780336-B1 | STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN | PASTEUR INSTITUT (FR) | 2017-07-19 | — | — | EP | disclosed |
| EP-2780336-A1 | STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN | Institut Pasteur (FR) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072896-A1 | STRUCTURAL VARIANTS OF MYCOLACTONES FOR USE IN MODULATING INFLAMMATION, IMMUNITY AND PAIN | INSTITUT PASTEUR (FR) | 2013-05-23 | — | — | WO | disclosed |