Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 19/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496910 | 0.88 | UTS2R (0.41) | UTS2RROCK2ROCK1 | |
| SCHEMBL10476389 | 0.87 | UTS2R (0.37) | UTS2RROCK2ROCK1 | |
| SCHEMBL1482616 | 0.87 | UTS2R (0.41) | UTS2RROCK2ROCK1 | |
| SCHEMBL1496996 | 0.87 | UTS2R (0.38) | UTS2RROCK2ROCK1 | |
| SCHEMBL1483181 | 0.86 | UTS2R (0.47) | UTS2RROCK2ROCK1 | |
| SCHEMBL1497187 | 0.86 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL1497206 | 0.85 | UTS2R (0.46) | UTS2R | |
| SCHEMBL1496894 | 0.85 | UTS2R (0.46) | UTS2R | |
| SCHEMBL1497037 | 0.85 | UTS2R (0.38) | UTS2R | |
| SCHEMBL1496877 | 0.84 | UTS2R (0.40) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |