Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.81 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.73 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 2/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | NPY1R | P25929 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970875 | 0.88 | CYP3A4 (1.00) | CYP3A4MEN1KMT2APTGER4CYP2C9 | |
| SCHEMBL10061503 | 0.82 | MAPT (0.77) | CYP3A4MEN1KMT2AMAPTLMNA | |
| SCHEMBL13912444 | 0.82 | CYP3A4 (0.77) | CYP3A4MEN1KMT2APTGER4CYP2C9 | |
| SCHEMBL30102560 | 0.81 | RXFP1 (0.73) | CYP3A4MEN1KMT2APTGER4CYP2C9 | |
| SCHEMBL17689194 | 0.81 | CYP3A4 (0.77) | CYP3A4MEN1KMT2APTGER4CYP2C9 | |
| SCHEMBL24688074 | 0.81 | RXFP1 (0.73) | CYP3A4MEN1KMT2APTGER4CYP2C9 | |
| SCHEMBL23722908 | 0.81 | CYP3A4 (1.00) | CYP3A4MEN1KMT2APTGER4CYP2C9 | |
| SCHEMBL14623959 | 0.81 | TACR3 (0.72) | CYP3A4MEN1KMT2APTGER4LMNA | |
| SCHEMBL17689185 | 0.80 | MEN1 (0.76) | CYP3A4MEN1KMT2ACYP2C9MAPT | |
| SCHEMBL13253446 | 0.80 | CYP3A4 (0.66) | CYP3A4MEN1KMT2APTGER4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275224-A1 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140275224-A1 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-09-18 | — | — | US | disclosed |
| WO-2013074059-A2 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275224-A1 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | CDA, DCTD, ADA | CYP3A4 2842/4885MEN1 2244/4885KMT2A 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.