Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497079 | 0.88 | USP2 (0.42) | USP2HIF1AEPAS1TSHROPRM1 | |
| SCHEMBL1482267 | 0.87 | USP2 (0.44) | USP2HIF1AEPAS1TSHROPRM1 | |
| SCHEMBL1496957 | 0.87 | KDM4E (0.43) | USP2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL1496934 | 0.86 | USP2 (0.43) | USP2HIF1AEPAS1TSHROPRM1 | |
| SCHEMBL1497036 | 0.85 | USP2 (0.45) | USP2HIF1AEPAS1TSHROPRM1 | |
| SCHEMBL8000862 | 0.85 | USP2 (0.48) | USP2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL13570016 | 0.85 | HDAC1 (0.47) | USP2TSHRNAMPTHDAC1 | |
| SCHEMBL1482239 | 0.85 | NAMPT (0.43) | USP2TSHROPRM1OPRD1NAMPT | |
| SCHEMBL7998655 | 0.85 | USP2 (0.46) | USP2TSHROPRM1OPRD1ALDH1A1 | |
| SCHEMBL1497080 | 0.84 | USP2 (0.44) | USP2TSHROPRM1OPRD1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |