SCHEMBL1497306

SCHEMBL1497306

CCc1ccccc1NCCCS(=O)(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.44
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 5/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
GRK2 P25098 2/20 0.40
HTT P42858 1/20 0.40
PTGS1 P23219 1/20 0.40
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11781512 0.83 DRD3 (0.49) POLBL3MBTL1ALDH1A1GAAMAPT
SCHEMBL9852005 0.82 MAPT (0.58) POLBHDAC3HDAC4HDAC1HDAC7
SCHEMBL10407866 0.81 POLB (0.54) POLBHDAC3HDAC4HDAC1HDAC7
SCHEMBL917776 0.80 MAPT (0.42) L3MBTL1ALDH1A1GAAMAPTHTT
SCHEMBL30844093 0.80 MAPT (0.42) L3MBTL1ALDH1A1GAAMAPTHTT
SCHEMBL10407954 0.80 POLB (0.53) POLBL3MBTL1ALDH1A1HTT
SCHEMBL10408718 0.80 POLB (0.53) POLBL3MBTL1ALDH1A1HTT
SCHEMBL3248990 0.80 POLB (0.53) POLBL3MBTL1ALDH1A1HTT
SCHEMBL27535051 0.79 POLB (0.47) POLBL3MBTL1ALDH1A1GAAMAPT
SCHEMBL3966040 0.79 POLB (0.60) POLBHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105431533-B Glycated hexapeptide oxidase and uses thereof 协和梅迪克斯株式会社 2019-06-28 CN disclosed
CN-104245931-B The stabilization method of cholesterol oxidase 协和梅迪克斯株式会社 2017-06-09 CN disclosed
CN-104321428-B The stabilization method of ascorbic acid oxidase 协和梅迪克斯株式会社 2017-05-31 CN disclosed
EP-2290362-B1 Synchronized analyte testing system HOFFMANN LA ROCHE (CH) 2013-01-23 EP disclosed
EP-1258728-B1 Synchronized analyte testing system HOFFMANN LA ROCHE (CH) 2012-05-30 EP disclosed
EP-2290362-A2 Synchronized analyte testing system Roche Diagnostics Operations, Inc. (US) 2011-03-02 EP disclosed
EP-1038176-B1 EMBOSSED TEST STRIP SYSTEM AMIRA MEDICAL (US) 2003-11-12 EP disclosed
EP-0937249-B1 SYNCHRONIZED ANALYTE TESTING SYSTEM AMIRA MEDICAL (US) 2002-12-18 EP disclosed
EP-1258728-A2 Synchronized analyte testing system Amira Medical (US) 2002-11-20 EP disclosed
EP-1038176-A2 EMBOSSED TEST STRIP SYSTEM Amira Medical (US) 2000-09-27 EP disclosed
US-6106780-A TO DETERMINE THE CHEMICAL AND BIOLOGICAL CONSTITUENTS IN BODILY FLUIDS. AMIRA MEDICAL (US) 2000-08-22 US disclosed
EP-0937249-A1 SYNCHRONIZED ANALYTE TESTING SYSTEM Mercury Diagnostics, Inc. (US) 1999-08-25 EP disclosed
WO-1999032883-A2 EMBOSSED TEST STRIP SYSTEM AMIRA MEDICAL (US) 1999-07-01 WO disclosed
US-5872713-A FOR DETECTING THE PRESENCE OF AN ANALYTE IN A SAMPLE MERCURY DIAGNOSTICS, INC. (US) 1999-02-16 US disclosed
WO-1998019159-A1 SYNCHRONIZED ANALYTE TESTING SYSTEM MERCURY DIAGNOSTICS, INC. (US) 1998-05-07 WO disclosed
US-4588435-A N-substituted amino propane sulfonic acid derivatives and plant growth regulating use EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1986-05-13 US disclosed