Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15015888 | 0.93 | S1PR1 (0.39) | BRD4S1PR1CA4SCN9ANPC1 | |
| SCHEMBL14973310 | 0.92 | S1PR1 (0.40) | S1PR1CA4SCN9ANPC1SMN1; SMN2 | |
| SCHEMBL14973282 | 0.92 | S1PR1 (0.38) | BRD4S1PR1CA4SCN9ANPC1 | |
| SCHEMBL14973257 | 0.90 | MAPT (0.42) | S1PR1NPC1SMN1; SMN2 | |
| SCHEMBL14973061 | 0.90 | HDAC4 (0.40) | BRD4S1PR1CA4SCN9A | |
| SCHEMBL14973150 | 0.90 | S1PR1 (0.40) | S1PR1CA4SCN9ANPC1SMN1; SMN2 | |
| SCHEMBL14973404 | 0.90 | S1PR1 (0.49) | S1PR1CA4NPC1SMN1; SMN2CA12 | |
| SCHEMBL14973038 | 0.89 | S1PR1 (0.40) | BRD4S1PR1NPC1SMN1; SMN2CA12 | |
| SCHEMBL14973206 | 0.89 | CA4 (0.49) | S1PR1CA4CA12CA1CA2 | |
| SCHEMBL14973068 | 0.88 | S1PR1 (0.40) | S1PR1SCN9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604602-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |
| US-20130137865-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137865-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137865-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137865-A1 | HETEROARYL-PYRAZOLE DERIVATIVE | GRIN2C, GRIN2B, GRIN3A | BRD4 792/4885S1PR1 2686/4885CA4 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.