Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | AKT1 | P31749 | 6/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | GPR39 | O43194 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14975821 | 0.88 | CNR1 (0.42) | CNR1CNR2AKT1AKT2GPR39 | |
| SCHEMBL14976320 | 0.88 | AKT1 (0.48) | CNR1CNR2AKT1AKT2CYP3A4 | |
| SCHEMBL14983721 | 0.86 | CNR1 (0.41) | CNR1CNR2AKT1AKT2GPR39 | |
| SCHEMBL14977466 | 0.86 | AKT1 (0.41) | CNR1CNR2AKT1AKT2KIT | |
| SCHEMBL14976254 | 0.86 | CNR1 (0.38) | CNR1CNR2AKT1AKT2KIT | |
| SCHEMBL14977374 | 0.84 | CNR1 (0.46) | CNR1CNR2AKT1AKT2GPR39 | |
| SCHEMBL14975799 | 0.83 | CNR1 (0.38) | CNR1CNR2AKT1AKT2KIT | |
| SCHEMBL14976215 | 0.82 | CNR1 (0.40) | CNR1CNR2AKT1AKT2GPR39 | |
| SCHEMBL14977603 | 0.80 | AKT1 (0.44) | CNR1CNR2AKT1AKT2KIT | |
| SCHEMBL14975849 | 0.80 | AKT1 (0.42) | CNR1CNR2AKT1AKT2GPR39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078254-A1 | BICYCLIC HETEROARYL DERIVATIVES AS KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2013-05-30 | — | — | WO | disclosed |