SCHEMBL14977309 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	3/20	0.55

▸	GAA	P10253	1/20	0.55

▸	SMN1; SMN2	Q16637	1/20	0.55

▸	RAB9A	P51151	4/20	0.54

▸	NOD1	Q9Y239	2/20	0.54

▸	GALR3	O60755	1/20	0.54

▸	TNF	P01375	1/20	0.54

▸	POLB	P06746	2/20	0.53

▸	NR2F2	P24468	1/20	0.53

▸	DHODH	Q02127	4/20	0.52

▸	NPC1	O15118	1/20	0.52

▸	KDM4E	B2RXH2	1/20	0.51

▸	RECQL	P46063	1/20	0.51

▸	MEN1	O00255	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL18850984	0.84	DHODH (0.58)	RAB9ANOD1TNFNR2F2DHODH
SCHEMBL18825149	0.84	DHODH (0.58)	RAB9ANOD1TNFNR2F2DHODH
Hydrochloric Acid SCHEMBL18825227	0.83	DHODH (0.57)	RAB9ANOD1TNFNR2F2DHODH
Hydrochloric Acid SCHEMBL18825124	0.83	DHODH (0.57)	RAB9ANOD1TNFNR2F2DHODH
SCHEMBL18825221	0.80	DHODH (0.57)	RAB9ANOD1TNFNR2F2DHODH
SCHEMBL18825222	0.80	DHODH (0.57)	RAB9ANOD1TNFNR2F2DHODH
SCHEMBL14985364	0.76	KMT2A (0.73)	KMT2AGAASMN1; SMN2RAB9ANOD1
SCHEMBL14977813	0.75	KMT2A (0.70)	KMT2AGAASMN1; SMN2RAB9ANOD1
SCHEMBL18825229	0.74	KMT2A (0.59)	KMT2AGAASMN1; SMN2RAB9ANOD1
SCHEMBL14985304	0.74	DHODH (0.81)	KMT2AGAASMN1; SMN2RAB9ANOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013078413-A1	MODULATORS OF LIPID STORAGE	THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US)	2013-05-30	—	—	WO	disclosed