Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 7/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977321 | 0.82 | DHODH (0.62) | DHODHKMT2A | |
| SCHEMBL2208532 | 0.73 | ELANE (0.53) | ELANEKMT2AGPR119 | |
| SCHEMBL12510895 | 0.73 | ELANE (0.53) | THRBKDM4ERECQLELANEGPR119 | |
| SCHEMBL2207579 | 0.73 | ELANE (0.52) | ELANEKMT2AGPR119 | |
| SCHEMBL14977475 | 0.71 | DHODH (0.40) | KDM4ERECQLDHODHKMT2A | |
| SCHEMBL14977651 | 0.69 | DHODH (0.47) | KDM4ERECQLDHODHKMT2A | |
| SCHEMBL4066257 | 0.68 | KMT2A (0.46) | LMNARECQLKMT2A | |
| SCHEMBL4066261 | 0.68 | KMT2A (0.46) | LMNARECQLKMT2A | |
| SCHEMBL4066265 | 0.68 | KMT2A (0.46) | LMNARECQLKMT2A | |
| SCHEMBL22594810 | 0.68 | KDM4E (0.59) | LMNATHRBKDM4EGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |