Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14911965 | 0.86 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL14930055 | 0.85 | CNR2 (0.61) | CNR2CNR1 | |
| Vicasinabin SCHEMBL14911648 | 0.84 | CNR2 (0.76) | CNR2 | |
| SCHEMBL14912079 | 0.84 | CNR2 (0.76) | CNR2CNR1 | |
| Vicasinabin SCHEMBL14912040 | 0.84 | CNR2 (0.76) | CNR2 | |
| Vicasinabin SCHEMBL14911479 | 0.84 | CNR2 (0.76) | CNR2 | |
| SCHEMBL14911639 | 0.84 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL14911644 | 0.84 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL14911990 | 0.84 | CNR2 (0.59) | CNR2CNR1 | |
| SCHEMBL14911598 | 0.83 | CNR2 (0.54) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782915-A1 | [1, 2, 3]TRIAZOLO [4, 5 -D]PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013076182-A1 | [1, 2, 3]TRIAZOLO [4, 5 -D] PYRIMIDINE DERIVATIVES AS AGONISTS OF THE CANNABINOID RECEPTOR 2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-05-30 | — | — | WO | disclosed |