SCHEMBL14977975

SCHEMBL14977975

CCOC(=O)/C=C/c1ccc(OC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.74
CA7 P43166 5/20 0.74
CA9 Q16790 5/20 0.74
CA14 Q9ULX7 5/20 0.74
CA1 P00915 4/20 0.74
CA2 P00918 3/20 0.74
ESR1 P03372 3/20 0.61
ABCG2 Q9UNQ0 3/20 0.56
MAOB P27338 2/20 0.56
CYP3A4 P08684 1/20 0.54
MAPT P10636 3/20 0.54
KDM4E B2RXH2 1/20 0.54
TTR P02766 1/20 0.53
DPP4 P27487 1/20 0.53
BCHE P06276 2/20 0.53
ESR2 Q92731 1/20 0.53
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA5B Q9Y2D0 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15255506 0.96 CA12 (0.68) CA12CA7CA9CA14CA1
SCHEMBL3610592 0.90 MAPT (0.57) CA12CA7CA9CA14CA1
Ethyl P-Coumarate SCHEMBL14262661 0.86 CA12 (1.00) CA12CA7CA9CA14CA1
Ethyl P-Coumarate SCHEMBL1341911 0.86 CA12 (1.00) CA12CA7CA9CA14CA1
Ethyl P-Coumarate SCHEMBL1341910 0.86 CA12 (1.00) CA12CA7CA9CA14CA1
SCHEMBL15623172 0.85 MAPT (0.73) CA12CA7CA9CA14CA1
SCHEMBL13768097 0.85 MAPT (0.73) CA12CA7CA9CA14CA1
SCHEMBL17061376 0.85 CA12 (0.85) CA12CA7CA9CA14CA1
SCHEMBL17061378 0.85 CA12 (0.85) CA12CA7CA9CA14CA1
SCHEMBL12367941 0.84 NPC1 (0.57) CA12CA7CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535769-B2 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, and oriented film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-17 US disclosed
US-8450517-B2 Photosensitive compound and its photosensitive polymer JNC CORPORATION (JP) 2013-05-28 US disclosed