SCHEMBL14979415

SCHEMBL14979415

c1ccc(-c2ccc(-c3ccc(-c4cnc(-n5c6ccccc6c6ccc7ccccc7c65)nc4)cc3-c3ccccc3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK10 P53779 1/20 0.33
MAP4K4 O95819 3/20 0.32
USP7 Q93009 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
FGFR1 P11362 1/20 0.32
TYK2 P29597 1/20 0.32
MINK1 Q8N4C8 1/20 0.32
SRPK1 Q96SB4 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PIK3CD O00329 1/20 0.31
PIK3CA P42336 1/20 0.31
PIK3CB P42338 1/20 0.31
MTOR P42345 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14979391 1.00 MAPK10 (0.33) MAPK10MAP4K4USP7HSD17B1HSD17B2
SCHEMBL14979313 0.93 TNF (0.35) MAPK10NPC1LMNAMAPTRECQL
SCHEMBL14979394 0.93 TNF (0.35) MAPK10NPC1LMNAMAPTRECQL
SCHEMBL14979316 0.91 TNF (0.35) MAPK10NPC1LMNAMAPTRECQL
SCHEMBL14979314 0.91 FGFR1 (0.35) MAPK10HSD17B1HSD17B2FGFR1CLK4
SCHEMBL14979357 0.91 NPC1 (0.37) MAPK10FGFR1NPC1LMNAMAPT
SCHEMBL14979421 0.90 FEN1 (0.36) NR3C1
SCHEMBL14979433 0.90 CA12 (0.35) MAP4K4FGFR1TYK2MINK1SRPK1
SCHEMBL14979401 0.89 NPC1 (0.35) MAPK10FGFR1NPC1LMNAMAPT
SCHEMBL14979397 0.89 NPC1 (0.35) MAPK10FGFR1NPC1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140316136-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME ROHM & HAAS ELECT MAT (KR) 2014-10-23 US disclosed
US-20140316136-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING SAME ROHM & HAAS ELECT MAT (KR) 2014-10-23 US disclosed
WO-2013073859-A1 NOVEL ORGANIC ELECTROLUMINESCENCE COMPOUNDS AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2013-05-23 WO disclosed