Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862323 | 0.93 | TAAR1 (0.44) | TAAR1GGPS1KCNH2CYP2D6PPARG | |
| SCHEMBL16802388 | 0.90 | TAAR1 (0.46) | TAAR1GGPS1KCNH2ACHELTA4H | |
| SCHEMBL10257788 | 0.90 | KMT2A (0.44) | GGPS1KCNH2CYP2D6PPARGPPARA | |
| SCHEMBL612432 | 0.85 | GGPS1 (0.44) | TAAR1GGPS1KCNH2ACHECYP2D6 | |
| SCHEMBL611253 | 0.83 | TAAR1 (0.45) | TAAR1GGPS1KCNH2ACHECYP2D6 | |
| SCHEMBL612001 | 0.83 | TAAR1 (0.47) | TAAR1GGPS1KCNH2ACHELTA4H | |
| SCHEMBL10258364 | 0.82 | TAAR1 (0.44) | TAAR1GGPS1KCNH2ACHECYP2D6 | |
| SCHEMBL16800378 | 0.81 | KMT2A (0.44) | GGPS1KCNH2CYP2D6PPARGPPARA | |
| SCHEMBL13881552 | 0.81 | TAAR1 (0.44) | TAAR1CYP2D6TSHRLTA4H | |
| SCHEMBL16802389 | 0.81 | GGPS1 (0.46) | TAAR1GGPS1KCNH2CYP2D6PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450527-B2 | Amine derivative compounds for treating ophthalmic diseases and disorders | ACUCELA INC. (US) | 2013-05-28 | — | — | US | disclosed |