Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | PITRM1 | Q5JRX3 | 4/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.45 |
| ▸ | FAP | Q12884 | 2/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22746096 | 1.00 | SLC1A2 (0.46) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| SCHEMBL8262232 | 1.00 | SLC1A2 (0.46) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| SCHEMBL22746095 | 1.00 | SLC1A2 (0.46) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| Hydrochloric Acid SCHEMBL4535083 | 0.98 | SLC1A2 (0.44) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| Hydrochloric Acid SCHEMBL29069903 | 0.98 | SLC1A2 (0.44) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| SCHEMBL1482506 | 0.98 | SLC1A2 (0.47) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| SCHEMBL31374917 | 0.98 | SLC1A2 (0.47) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| Hydrochloric Acid SCHEMBL28004131 | 0.95 | SLC1A2 (0.46) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| Hydrochloric Acid SCHEMBL15412292 | 0.95 | SLC1A2 (0.46) | SLC1A2SLC1A1DPP4PITRM1DPP8 | |
| SCHEMBL23462330 | 0.93 | SLC1A2 (0.47) | SLC1A2SLC1A1DPP4PITRM1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306790-A | Amide derivative, composition and use thereof | 深圳市塔吉瑞生物医药有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-9328138-B2 | HCV NS3 protease inhibitors | MSD ITALIA S.R.L. (IT) | 2016-05-03 | — | — | US | disclosed |
| US-9328138-B2 | HCV NS3 protease inhibitors | MSD ITALIA S.R.L. (IT) | 2016-05-03 | — | — | US | disclosed |
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
| WO-2013074386-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | HAVCR2, GTF3C3, CTSC | SLC1A2 4616/4885SLC1A1 3846/4885DPP4 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.