Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.63 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021118 | 0.92 | FFAR1 (0.64) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL14273217 | 0.91 | FFAR1 (0.63) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL12021109 | 0.90 | FFAR1 (0.62) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL16326316 | 0.90 | FFAR1 (0.75) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL12348753 | 0.89 | FFAR1 (0.61) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL13318210 | 0.85 | FFAR1 (0.68) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL12020986 | 0.85 | FFAR1 (0.68) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL13350442 | 0.85 | FFAR1 (0.65) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL14286071 | 0.84 | FFAR1 (0.62) | FFAR1MRGPRX4PPARDPPARAPPARG | |
| SCHEMBL12021108 | 0.84 | FFAR1 (0.64) | FFAR1MRGPRX4PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450522-B2 | Conformationally constrained carboxylic acid derivatives useful for treating metabolic disorders | AMGEN INC. (US) | 2013-05-28 | — | — | US | disclosed |