Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668921 | 0.80 | CHRNA7 (0.42) | IDO1CHRNA7ACHETDP1MAOA | |
| SCHEMBL8286101 | 0.78 | SLC6A4 (0.59) | CHRNA7ACHETDP1MAOAMAOB | |
| SCHEMBL3863807 | 0.78 | SLC6A4 (0.59) | CHRNA7ACHETDP1MAOAMAOB | |
| SCHEMBL4707636 | 0.78 | CYP1A2 (0.41) | CHRNA7ACHETDP1MAOAMAOB | |
| SCHEMBL3865060 | 0.78 | SLC6A4 (0.59) | CHRNA7ACHETDP1MAOAMAOB | |
| SCHEMBL14981091 | 0.77 | ANPEP (0.50) | ANPEPIDO1ENPEPTDP1SLC6A4 | |
| Hydrochloric Acid SCHEMBL4933575 | 0.76 | SLC6A4 (0.57) | CHRNA7ACHETDP1MAOAMAOB | |
| SCHEMBL3636547 | 0.76 | CHRNA7 (0.39) | ANPEPCHRNA7ACHETDP1MAOA | |
| SCHEMBL17619269 | 0.76 | CHRNA7 (0.39) | ANPEPCHRNA7ACHETDP1MAOA | |
| SCHEMBL12195403 | 0.76 | CHRNA7 (0.39) | ANPEPCHRNA7ACHETDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2634191-B1 | Process for preparing derivatives of thienopyrimidinedione | GLENMARK PHARMACEUTICALS SA (CH) | 2014-12-24 | — | — | EP | disclosed |
| EP-2634191-A1 | Process for preparing derivatives of thienopyrimidinedione | Glenmark Pharmaceuticals S.A. (CH) | 2013-09-04 | — | — | EP | disclosed |
| EP-2411396-B1 | THIENOPYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2411397-B1 | ISOTHIAZOLO-PYRIMIDINEDIONE DERIVATIVES AS TRPA1 MODULATORS | GLENMARK PHARMACEUTICALS SA (CH) | 2013-05-29 | — | — | EP | disclosed |