Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15451125 | 0.90 | BACE1 (0.66) | BACE1BACE2 | |
| SCHEMBL4082664 | 0.85 | BACE1 (0.74) | BACE1BACE2 | |
| SCHEMBL12521606 | 0.84 | BACE1 (0.76) | BACE1BACE2 | |
| SCHEMBL4073739 | 0.84 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL4073989 | 0.84 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL6524838 | 0.84 | BACE1 (0.67) | BACE1BACE2 | |
| SCHEMBL12521615 | 0.84 | BACE1 (0.77) | BACE1BACE2 | |
| SCHEMBL12521607 | 0.83 | BACE1 (0.83) | BACE1BACE2 | |
| SCHEMBL12521921 | 0.82 | BACE1 (0.71) | BACE1BACE2 | |
| SCHEMBL4077181 | 0.82 | BACE1 (0.69) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2612854-A1 | Aminothiazolidine and aminotetrahydrothiazepine derivatives as BACE 1 inhibitors | Shionogi&Co., Ltd. (JP) | 2013-07-10 | — | — | EP | disclosed |
| EP-2597087-A1 | Dihydrooxazine and tetrahydropyrimidine derivatives as BACE 1 inhibitors | Shionogi&Co., Ltd. (JP) | 2013-05-29 | — | — | EP | disclosed |