Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154963 | 0.88 | BACE1 (0.67) | BACE1APP | |
| SCHEMBL10156032 | 0.82 | BACE1 (0.78) | BACE1APP | |
| SCHEMBL10155487 | 0.82 | BACE1 (0.66) | BACE1APP | |
| SCHEMBL10154657 | 0.82 | BACE1 (0.84) | BACE1APP | |
| SCHEMBL15041112 | 0.82 | BACE1 (0.75) | BACE1APP | |
| SCHEMBL10156221 | 0.81 | BACE1 (0.71) | BACE1APP | |
| SCHEMBL10154749 | 0.81 | BACE1 (0.71) | BACE1APP | |
| SCHEMBL10158144 | 0.80 | BACE1 (0.72) | BACE1APP | |
| SCHEMBL10155565 | 0.80 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL10154717 | 0.80 | BACE1 (0.76) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2597087-A1 | Dihydrooxazine and tetrahydropyrimidine derivatives as BACE 1 inhibitors | Shionogi&Co., Ltd. (JP) | 2013-05-29 | — | — | EP | disclosed |