Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431976 | 0.87 | BTK (0.61) | BTK | |
| SCHEMBL1432420 | 0.86 | BTK (0.66) | BTK | |
| SCHEMBL3143421 | 0.86 | BTK (0.61) | BTK | |
| SCHEMBL3147167 | 0.85 | BTK (0.64) | BTK | |
| SCHEMBL3143542 | 0.85 | BTK (0.67) | BTK | |
| SCHEMBL3139137 | 0.84 | BTK (0.60) | BTK | |
| SCHEMBL3131615 | 0.84 | BTK (0.72) | BTK | |
| SCHEMBL3134955 | 0.84 | BTK (0.63) | BTK | |
| SCHEMBL3147107 | 0.84 | BTK (0.68) | BTK | |
| SCHEMBL3143694 | 0.84 | BTK (0.68) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300459-B1 | NOVEL PHENYLPYRAZINONES AS KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-05-29 | — | — | EP | disclosed |