Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143934 | 0.94 | BTK (0.83) | BTK | |
| SCHEMBL1432650 | 0.93 | BTK (0.88) | BTK | |
| SCHEMBL3138829 | 0.92 | BTK (0.81) | BTK | |
| SCHEMBL3143279 | 0.92 | BTK (0.87) | BTK | |
| SCHEMBL3143519 | 0.92 | BTK (0.87) | BTK | |
| SCHEMBL3143502 | 0.92 | BTK (1.00) | BTK | |
| SCHEMBL3144070 | 0.92 | BTK (0.84) | BTK | |
| SCHEMBL3143417 | 0.91 | BTK (0.85) | BTK | |
| SCHEMBL1432874 | 0.90 | BTK (0.84) | BTK | |
| SCHEMBL3131519 | 0.90 | BTK (0.77) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300459-B1 | NOVEL PHENYLPYRAZINONES AS KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-05-29 | — | — | EP | disclosed |