Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129200 | 0.89 | BTK (0.70) | BTK | |
| SCHEMBL3131615 | 0.83 | BTK (0.72) | BTK | |
| SCHEMBL3139251 | 0.81 | BTK (0.79) | BTK | |
| SCHEMBL3134934 | 0.81 | BTK (0.69) | BTK | |
| SCHEMBL1431535 | 0.81 | BTK (0.69) | BTK | |
| SCHEMBL1431519 | 0.81 | BTK (0.83) | BTK | |
| SCHEMBL1431576 | 0.78 | BTK (0.70) | BTK | |
| SCHEMBL3131642 | 0.78 | BTK (0.87) | BTK | |
| SCHEMBL14980892 | 0.78 | BTK (0.59) | BTK | |
| SCHEMBL3128926 | 0.76 | BTK (0.76) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300459-B1 | NOVEL PHENYLPYRAZINONES AS KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-05-29 | — | — | EP | disclosed |