⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844984 | 1.00 | — | — | |
| SCHEMBL8223087 | 1.00 | — | — | |
| SCHEMBL2666878 | 1.00 | — | — | |
| SCHEMBL8225002 | 1.00 | — | — | |
| SCHEMBL14555171 | 0.87 | TLR4 (0.38) | — | |
| SCHEMBL16151871 | 0.86 | CA1 (0.40) | — | |
| SCHEMBL14646885 | 0.86 | CA1 (0.40) | — | |
| SCHEMBL21038566 | 0.86 | CA1 (0.40) | — | |
| SCHEMBL6127788 | 0.86 | CA1 (0.40) | — | |
| SCHEMBL4843048 | 0.86 | CA1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2063887-B1 | NEW SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF | UNIV MICHIGAN (US) | 2013-05-29 | — | — | EP | disclosed |