Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 13/20 | 0.76 |
| ▸ | BRAF | P15056 | 13/20 | 0.76 |
| ▸ | CSF1R | P07333 | 5/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | KIT | P10721 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893691 | 0.87 | BRAF (1.00) | RAF1BRAFCSF1RKDR | |
| SCHEMBL13209798 | 0.86 | RAF1 (1.00) | RAF1BRAFKDR | |
| SCHEMBL13209793 | 0.86 | BRAF (1.00) | RAF1BRAFKDR | |
| SCHEMBL13884456 | 0.85 | CSF1R (0.68) | RAF1BRAFCSF1RPDGFRBKIT | |
| SCHEMBL3056890 | 0.84 | RAF1 (0.64) | RAF1BRAFCSF1RPDGFRBKIT | |
| SCHEMBL2890385 | 0.84 | BRAF (1.00) | RAF1BRAFKDR | |
| SCHEMBL13209800 | 0.84 | RAF1 (0.83) | RAF1BRAFCSF1RKDR | |
| SCHEMBL3017839 | 0.83 | BRAF (1.00) | RAF1BRAFKCNH2 | |
| SCHEMBL3054574 | 0.83 | RAF1 (0.62) | RAF1BRAFCSF1RPDGFRBKIT | |
| SCHEMBL3056150 | 0.83 | CSF1R (0.87) | RAF1BRAFCSF1RPDGFRBKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258365-B1 | USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2013-05-29 | — | — | EP | disclosed |