Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM6B | O15054 | 3/20 | 0.77 |
| ▸ | KDM4A | O75164 | 2/20 | 0.77 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.49 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.49 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985134 | 0.91 | KDM6B (0.62) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14981984 | 0.89 | KDM6B (0.61) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14981985 | 0.87 | KDM6B (1.00) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14981960 | 0.84 | KDM4A (0.54) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14985030 | 0.83 | KDM6B (0.56) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14985132 | 0.83 | KDM6B (0.53) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14985133 | 0.80 | KDM6B (0.63) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14985029 | 0.80 | KDM4E (0.66) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14985161 | 0.78 | KDM6B (0.80) | KDM6BKDM4AKDM2AKDM4EKDM4C | |
| SCHEMBL14985090 | 0.78 | KDM6B (0.57) | KDM6BKDM4AKDM2AKDM4EKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735622-B2 | Histone demethylase inhibitors and methods for using the same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130137720-A1 | HISTONE DEMETHYLASE INHIBITORS AND METHODS FOR USING THE SAME | The Regents of the University of Colorado, a body corporated (US) | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137720-A1 | HISTONE DEMETHYLASE INHIBITORS AND METHODS FOR USING THE SAME | KDM1A, KDM3A, KDM7A | KDM6B 15/4885KDM4A 9/4885KDM2A 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.