Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.53 |
| ▸ | GYS2 | P54840 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | PDE9A | O76083 | 1/20 | 0.50 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12181444 | 0.84 | PDE4D (0.53) | PTPN2PTPN1ACP1GYS2IKBKB | |
| SCHEMBL13629645 | 0.83 | POLB (0.63) | PTPN2PTPN1ACP1GYS2PDE4D | |
| SCHEMBL4456335 | 0.72 | POLB (0.61) | PTPN2PTPN1ACP1 | |
| SCHEMBL4456338 | 0.72 | POLB (0.61) | PTPN2PTPN1ACP1 | |
| SCHEMBL23790926 | 0.70 | PTPN1 (0.85) | PTPN2PTPN1ACP1IKBKB | |
| SCHEMBL6444051 | 0.69 | PTPN1 (0.68) | PTPN2PTPN1ACP1IKBKB | |
| SCHEMBL22335213 | 0.69 | PTPN1 (1.00) | PTPN2PTPN1ACP1IKBKB | |
| SCHEMBL10014345 | 0.69 | PDE4D (0.74) | PTPN2PTPN1ACP1PDE4DPDE5A | |
| SCHEMBL13487370 | 0.69 | PDE4D (0.80) | PTPN2PTPN1PDE4DPDE5APDE9A | |
| SCHEMBL24433073 | 0.69 | PDE4D (0.73) | PTPN2PTPN1ACP1GYS2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078372-A1 | COMPOSITIONS AND METHODS FOR INHIBITING MUSCLE ATROPHY AND INDUCING MUSCLE HYPERTROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-05-30 | — | — | WO | disclosed |