⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268094 | 1.00 | — | — | |
| SCHEMBL13640593 | 1.00 | — | — | |
| SCHEMBL15096738 | 0.80 | — | — | |
| SCHEMBL14981490 | 0.77 | HCAR2 (0.30) | — | |
| SCHEMBL18845140 | 0.77 | HCAR2 (0.30) | — | |
| SCHEMBL23774821 | 0.76 | — | — | |
| SCHEMBL17740128 | 0.76 | — | — | |
| SCHEMBL17170571 | 0.76 | — | — | |
| SCHEMBL29311648 | 0.76 | — | — | |
| SCHEMBL23220187 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759994-B2 | Luminogenic transition metal-based pyridyl complex and its use | CITY UNIVERSITY OF HONG KONG (HK) | 2020-09-01 | — | — | US | disclosed |
| US-20180142144-A1 | LUMINOGENIC TRANSITION METAL-BASED PYRIDYL COMPLEX AND ITS USE | CITY UNIVERSITY OF HONG KONG (HK) | 2018-05-24 | — | — | US | disclosed |
| US-9801943-B2 | Method for in vivo targeting of nanoparticles via bioorthogonal copper-free click chemistry | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-10-31 | — | — | US | disclosed |
| US-9801943-B2 | Method for in vivo targeting of nanoparticles via bioorthogonal copper-free click chemistry | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-10-31 | — | — | US | disclosed |
| US-20160214917-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2016-07-28 | — | — | US | disclosed |
| WO-2015200080-A1 | SITE SPECIFIC PROTEIN MODIFICATIONS | NOVARTIS AG (CH) | 2015-12-30 | — | — | WO | disclosed |
| US-9222940-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2015-12-29 | — | — | US | disclosed |
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | Anglachem Inc. (CA) | 2015-10-15 | — | — | US | disclosed |
| US-20150125892-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. (NL) | 2015-05-07 | — | — | US | disclosed |
| US-8859629-B2 | Fused cyclooctyne compounds and their use in metal-free click reactions | SYNAFFIX B.V. (NL) | 2014-10-14 | — | — | US | disclosed |
| US-20130251784-A1 | METHOD FOR IN VIVO TARGETING OF NANOPARTICLES VIA BIOORTHOGONAL COPPER-FREE CLICK CHEMISTRY | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-09-26 | — | — | US | disclosed |
| US-20130251784-A1 | METHOD FOR IN VIVO TARGETING OF NANOPARTICLES VIA BIOORTHOGONAL COPPER-FREE CLICK CHEMISTRY | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-09-26 | — | — | US | disclosed |
| US-20130137763-A1 | FUSED CYCLOOCTYNE COMPOUNDS AND THEIR USE IN METAL-FREE CLICK REACTIONS | SYNAFFIX B.V. | 2013-05-30 | — | — | US | disclosed |