Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.76 |
| ▸ | CTSK | P43235 | 5/20 | 0.76 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075463 | 1.00 | CTSC (0.76) | CTSCCTSKKCNH2 | |
| Trifluoroacetic Acid SCHEMBL2075386 | 0.95 | CTSC (0.73) | CTSCCTSKKCNH2 | |
| SCHEMBL1499026 | 0.92 | CTSC (0.76) | CTSCCTSKKCNH2 | |
| SCHEMBL2075023 | 0.92 | CTSC (0.76) | CTSCCTSKKCNH2 | |
| SCHEMBL8045417 | 0.92 | CTSC (0.72) | CTSCCTSKKCNH2 | |
| SCHEMBL2074964 | 0.89 | CTSC (0.69) | CTSCCTSKKCNH2 | |
| SCHEMBL1499053 | 0.89 | CTSC (0.69) | CTSCCTSKKCNH2 | |
| SCHEMBL1499047 | 0.87 | CTSC (1.00) | CTSCCTSKKCNH2 | |
| SCHEMBL2072228 | 0.87 | CTSC (1.00) | CTSCCTSKKCNH2 | |
| SCHEMBL8032292 | 0.87 | CTSC (1.00) | CTSCCTSKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011506421-A | — | — | 2011-03-03 | — | — | JP | claimed |
| EP-2231597-A1 | PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS | AstraZeneca AB (SE) | 2010-09-29 | — | — | EP | claimed |
| WO-2009074829-A1 | PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS | ASTRAZENECA AB (SE) | 2009-06-18 | — | — | WO | claimed |
| EP-2231597-A1 | PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS | AstraZeneca AB (SE) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009074829-A1 | PEPTIDYL NITRILES AND USE THEREOF AS DIPEPTIDYL PEPTIDASE I INHIBITORS | ASTRAZENECA AB (SE) | 2009-06-18 | — | — | WO | disclosed |