SCHEMBL1499646

SCHEMBL1499646

CC(=O)NCCCCC[O]

nearest known ligand 0.80

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.80
MAPK1 P28482 1/20 0.80
HIF1A Q16665 1/20 0.80
PAOX Q6QHF9 3/20 0.64
ADRA1A P35348 1/20 0.61
TSHR P16473 1/20 0.46
EPHX1 P07099 5/20 0.44
ALDH1A1 P00352 2/20 0.44
NAMPT P43490 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CASP2 P42575 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1499634 1.00 KDM4E (0.80) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1499658 0.97
SCHEMBL1446623 0.90
SCHEMBL1847535 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14740132 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL6516953 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14740196 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL10937726 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14739904 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL1900654 0.89 KDM4E (1.00) KDM4EMAPK1HIF1APAOXADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-12-07 US claimed
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2019-04-11 US claimed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US claimed
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 US claimed
US-9060518-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-06-23 US claimed
JP-2011509971-A 2011-03-31 JP claimed
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2011-03-03 US claimed
EP-2234489-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE Bayer CropScience AG (DE) 2010-10-06 EP claimed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO claimed
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2019-01-29 US disclosed
EP-3262940-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND AN INSECTICIDE ACTIVE SUBSTANCE Bayer Intellectual Property GmbH (DE) 2018-01-03 EP disclosed
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AG (DE) 2015-09-17 US disclosed
US-9060518-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2015-06-23 US disclosed
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2011-03-03 US disclosed
WO-2009090181-A2 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE BAYER CROPSCIENCE SA (FR) 2009-07-23 WO disclosed
EP-1426371-B1 TETRAZOYL OXIME DERIVATIVES AND AGROCHEMICALS CONTAINING THE SAME AS THE ACTIVE INGREDIENT NIPPON SODA CO (JP) 2008-12-03 EP disclosed
US-20070105926-A1 Tetrazoyloxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD (JP) 2007-05-10 US disclosed
US-7183299-B2 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient NIPPON SODA CO., LTD. (JP) 2007-02-27 US disclosed
US-20050070439-A1 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-03-31 US disclosed
EP-1426371-A1 TETRAZOYL OXIME DERIVATIVE AND AGRICULTURAL CHEMICAL CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK AND CHEMICALS, INC. (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105926-A1 Tetrazoyloxime derivative and agricultural chemical containing the same as active ingredient PAOX, TH, CYP2E1 KDM4E 913/4885MAPK1 935/4885HIF1A 2376/4885
US-11191270-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-20110052555-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-20150257387-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-20050070439-A1 Tetrazoyl oxime derivative and agricultural chemical containing the same as active ingredient TH, CYP2E1, PAOX KDM4E 1022/4885MAPK1 894/4885HIF1A 1439/4885
US-20190104736-A1 PESTICIDE COMPOSITION COMPRISING A TETRAZOLYLOXIME DERIVATIVE AND A FUNGICIDE OR AN INSECTICIDE ACTIVE SUBSTANCE DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885
US-10188106-B2 Pesticide composition comprising a tetrazolyloxime derivative and a fungicide or an insecticide active substance DDT, TH, PRDX5 KDM4E 2173/4885MAPK1 4598/4885HIF1A 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.