Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 19/20 | 0.60 |
| ▸ | EGLN3 | Q9H6Z9 | 16/20 | 0.60 |
| ▸ | EGLN2 | Q96KS0 | 15/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960439 | 0.92 | EGLN1 (0.71) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL12917981 | 0.91 | EGLN1 (0.59) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL963981 | 0.91 | EGLN1 (0.59) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL964873 | 0.90 | EGLN1 (0.59) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL960713 | 0.90 | EGLN1 (0.58) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL959931 | 0.88 | EGLN1 (0.76) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL960180 | 0.88 | EGLN1 (0.56) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL961600 | 0.86 | EGLN1 (0.75) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL13692621 | 0.84 | EGLN1 (0.59) | EGLN1EGLN3EGLN2CYSLTR2 | |
| SCHEMBL960442 | 0.81 | EGLN1 (0.71) | EGLN1EGLN3EGLN2CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257169-B1 | TETRAHYDROTHIENO PYRIDINES | MERCK SHARP & DOHME (US) | 2013-06-05 | — | — | EP | disclosed |