Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101150 | 1.00 | LARS1 (0.52) | LARS1F2ALDH1A1PLGF10 | |
| SCHEMBL15000276 | 0.92 | LARS1 (0.53) | LARS1F2ALDH1A1PLGKDM4E | |
| SCHEMBL3085973 | 0.92 | LARS1 (0.53) | LARS1F2ALDH1A1PLGKDM4E | |
| SCHEMBL3093732 | 0.91 | LARS1 (0.44) | LARS1F2ALDH1A1PLGF10 | |
| SCHEMBL13152388 | 0.91 | LARS1 (0.50) | LARS1F2ALDH1A1 | |
| SCHEMBL18383338 | 0.91 | LARS1 (0.50) | LARS1F2ALDH1A1 | |
| SCHEMBL18387777 | 0.91 | LARS1 (0.50) | LARS1F2KMT2A | |
| SCHEMBL15000058 | 0.90 | LARS1 (0.50) | LARS1F2PLGF10PLAT | |
| SCHEMBL15000268 | 0.90 | LARS1 (0.50) | LARS1F2ALDH1A1KDM4EKMT2A | |
| SCHEMBL15000247 | 0.90 | LARS1 (0.49) | LARS1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461209-B2 | Malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |