Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14999879 | 0.93 | JAK1 (0.80) | JAK1JAK2 | |
| SCHEMBL2273875 | 0.91 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL2292014 | 0.90 | JAK1 (0.82) | JAK1JAK2 | |
| SCHEMBL2295826 | 0.90 | JAK1 (0.81) | JAK1JAK2 | |
| SCHEMBL2297848 | 0.89 | JAK1 (0.80) | JAK1JAK2 | |
| SCHEMBL12385273 | 0.89 | JAK1 (0.76) | JAK1JAK2 | |
| SCHEMBL2296914 | 0.88 | JAK1 (0.93) | JAK1JAK2 | |
| SCHEMBL2290865 | 0.87 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL2277642 | 0.86 | JAK1 (1.00) | JAK1JAK2 | |
| SCHEMBL2297480 | 0.86 | JAK1 (0.79) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461328-B2 | Tricyclic heterocyclic compounds, compositions and methods of use thereof | GENENTECH, INC. (US) | 2013-06-11 | — | — | US | disclosed |