SCHEMBL150053

SCHEMBL150053

O=C(O)Cn1c2ccccc2c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 1.00
GLA P06280 2/20 0.81
FABP4 P15090 3/20 0.66
FABP5 Q01469 3/20 0.66
FABP3 P05413 1/20 0.66
APEX1 P27695 1/20 0.64
PTGDR2 Q9Y5Y4 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP2C19 P33261 1/20 0.60
ALDH1A1 P00352 1/20 0.60
MAPK1 P28482 1/20 0.60
STAT3 P40763 1/20 0.60
POLB P06746 1/20 0.60
THRB P10828 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
MEN1 O00255 1/20 0.60
CASP1 P29466 1/20 0.60
CASP7 P55210 1/20 0.60
KMT2A Q03164 1/20 0.60
HSD17B10 Q99714 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859932 1.00 KDM4E (1.00) KDM4EGLAFABP4FABP5FABP3
Cridanimod SCHEMBL29373385 0.90 GLA (1.00) KDM4EGLAFABP4FABP5FABP3
Cridanimod SCHEMBL3372087 0.90 GLA (1.00) KDM4EGLAFABP4FABP5FABP3
Cridanimod SCHEMBL3801665 0.90 GLA (1.00) KDM4EGLAFABP4FABP5FABP3
Cridanimod SCHEMBL27895128 0.88 GLA (0.96) KDM4EGLAFABP4FABP5FABP3
Cridanimod SCHEMBL3375819 0.88 GLA (0.96) KDM4EGLAFABP4FABP5FABP3
Cridanimod SCHEMBL3375823 0.88 GLA (0.96) KDM4EGLAFABP4FABP5FABP3
SCHEMBL23520647 0.87 KDM4E (0.76) KDM4EGLAFABP4FABP5FABP3
SCHEMBL5151521 0.86 KDM4E (0.74) KDM4EGLAFABP4FABP5FABP3
SCHEMBL1120319 0.85 KDM4E (0.72) KDM4EGLAFABP4FABP5FABP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119529246-A Conductive material, preparation method and related application thereof 澳门大学 2025-02-28 CN claimed
CN-117337115-A Lead-tin mixed perovskite solar cell based on self-assembled monolayer and preparation method thereof 河南大学 2024-01-02 CN claimed
CN-112940227-B Polycarbazole with side chain containing TEMPO and preparation method and application thereof 浙江工业大学 2022-09-23 CN claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-110204559-B Carbazolyl-containing triazolothiadiazole derivative and preparation method thereof 陕西科技大学 2021-06-29 CN claimed
CN-112940227-A Polycarbazole with side chain containing TEMPO and preparation method and application thereof 浙江工业大学 2021-06-11 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
CN-106967213-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2019-11-05 CN claimed
CN-110204559-A A kind of carbazolyl-containing Triterpenic acid derivative and preparation method thereof 陕西科技大学 2019-09-06 CN claimed
CN-106967213-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2017-07-21 CN claimed
EP-1569929-B9 COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS VIROCHEM PHARMA INC (CA) 2011-09-14 EP claimed
EP-1427386-B1 PRODUCTS FOR PREVENTING PENETRATION INTO THE SKIN YISSUM RES DEV CO (IL) 2010-10-20 EP claimed
US-20100171923-A1 LACTAM POLYMER DERIVATIVES JOHSNON & JOHNSON VISION CARE, INC. 2010-07-08 US claimed
US-7736630-B2 Products for preventing penetration into the skin YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2010-06-15 US claimed
EP-1569929-B1 COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS VIROCHEM PHARMA INC (CA) 2010-05-05 EP claimed
US-20070290174-A1 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. 2007-12-20 US claimed
CN-101065407-A Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE (US) 2007-10-31 CN claimed
EP-1799724-A2 LACTAM POLYMER DERIVATIVES Johnson and Johnson Vision Care, Inc. (US) 2007-06-27 EP claimed
WO-2006039276-A2 LACTAM POLYMER DERIVATIVES JOHNSON & JOHNSON VISION CARE, INC. (US) 2006-04-13 WO claimed
US-20060069235-A1 Lactam polymer derivatives JOHNSON & JOHNSON VISION CARE, INC. 2006-03-30 US claimed