Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 19/20 | 0.67 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15005622 | 0.95 | CHRM3 (0.66) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4896417 | 0.94 | CHRM3 (0.64) | CHRM3CHRM2CHRM1 | |
| SCHEMBL12172651 | 0.90 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL14015868 | 0.86 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9967808 | 0.86 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4891590 | 0.85 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4887549 | 0.85 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL9967815 | 0.82 | CHRM3 (0.63) | CHRM3CHRM2CHRM1 | |
| SCHEMBL15015231 | 0.81 | CHRM3 (0.70) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4897583 | 0.81 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146957-B1 | QUATERNARY AMMONIUM COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE INC (US) | 2013-06-12 | — | — | EP | disclosed |