Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 16/20 | 0.84 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.48 |
| ▸ | AKT1 | P31749 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15025981 | 0.91 | GRM5 (1.00) | GRM5RPS6KB1AKT1 | |
| SCHEMBL15025847 | 0.85 | GRM5 (0.78) | GRM5RPS6KB1AKT1 | |
| SCHEMBL15025982 | 0.84 | GRM5 (0.73) | GRM5RPS6KB1AKT1 | |
| SCHEMBL15025648 | 0.84 | GRM5 (1.00) | GRM5 | |
| SCHEMBL15025905 | 0.84 | GRM5 (0.90) | GRM5 | |
| SCHEMBL15115109 | 0.83 | GRM5 (0.60) | GRM5 | |
| SCHEMBL14982336 | 0.83 | GRM5 (0.59) | GRM5 | |
| SCHEMBL15025660 | 0.83 | GRM5 (0.68) | GRM5RPS6KB1AKT1 | |
| SCHEMBL15115154 | 0.82 | GRM5 (0.58) | GRM5 | |
| SCHEMBL15007324 | 0.81 | GRM5 (0.64) | GRM5RPS6KB1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846948-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846948-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20130150355-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
| US-20130150355-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150355-A1 | NOVEL COMPOUNDS | GRM5, GRIN2A, GRIN1 | GRM5 1/4885RPS6KB1 1038/4885AKT1 1307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.