Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 2/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.36 |
| ▸ | CPA3 | P15088 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8815418 | 0.79 | FOLH1 (0.45) | FOLH1TDP1GABRR1GABRR2BLM | |
| SCHEMBL12420003 | 0.78 | TDP1 (0.61) | TDP1GABRR1GABRR2BLMGABRR3 | |
| SCHEMBL28916883 | 0.77 | FOLH1 (0.48) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL8389180 | 0.77 | FOLH1 (0.58) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL17669226 | 0.75 | FOLH1 (0.56) | FOLH1TDP1BLMTSHRCPA1 | |
| SCHEMBL8385324 | 0.75 | FOLH1 (0.56) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL21802279 | 0.75 | FOLH1 (0.75) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL164322 | 0.75 | FOLH1 (0.75) | FOLH1TDP1CPA1CPB1CPA3 | |
| SCHEMBL23777853 | 0.73 | PPARG (0.56) | TDP1BLMLMNATSHRAPEX1 | |
| SCHEMBL7975761 | 0.72 | FOLH1 (0.52) | FOLH1BLMTSHRCPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292687-B1 | Improved vulcanisable guanidine-free mixtures containing ethylene acrylate (AEM), polyacrylate (ACM) and/or hydrogenated acrylnitrile (HNBR)-based rubbers compounds, vulcanisates, prepared by cross-linking this vulcanisable mixtures and their use | RHEIN CHEMIE RHEINAU GMBH (DE) | 2012-07-25 | — | — | EP | disclosed |
| US-20110183875-A1 | Vulcanisable guanidine-free mixtures containing ethylene acrylate (AEM), polyacrylate (ACM) and/or hydrogenated acrylnitrile (HNBR)-based rubbers compounds, vulcanisates, prepared by cross-linking this vulcanisable mixtures and their use | RHEIN CHEMIE RHEINAU GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
| EP-2033989-B1 | Safer curing systems for acrylic rubbers compounds | RHEIN CHEMIE RHEINAU GMBH (DE) | 2011-06-29 | — | — | EP | disclosed |
| EP-2292687-A1 | Improved vulcanisable guanidine-free mixtures containing ethylene acrylate (AEM), polyacrylate (ACM) and/or hydrogenated acrylnitrile (HNBR)-based rubbers compounds, vulcanisates, prepared by cross-linking this vulcanisable mixtures and their use | Rhein Chemie Rheinau GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |
| EP-2033989-A1 | Safer curing systems for acrylic rubbers compounds | Rhein Chemie Rheinau GmbH (DE) | 2009-03-11 | — | — | EP | disclosed |