Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.48 |
| ▸ | FAP | Q12884 | 14/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.48 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15386518 | 0.91 | DPP4 (0.56) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL13263476 | 0.91 | DPP4 (0.56) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL15334874 | 0.87 | DPP4 (0.33) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL15028065 | 0.84 | DPP4 (0.50) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL15028066 | 0.80 | DPP4 (0.51) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL15028072 | 0.79 | DPP4 (0.58) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL15712058 | 0.77 | DPP4 (0.47) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL16789728 | 0.73 | PSEN1 (0.32) | — | |
| SCHEMBL12343993 | 0.72 | DPP4 (0.68) | DPP4FAPDPP7DPP8DPP9 | |
| SCHEMBL18082886 | 0.72 | DPP4 (0.68) | DPP4FAPDPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150292-A1 | Soft Protease Inhibitors and Pro-Soft Forms Thereof | TRUSTEES OF TUFTS COLLEGE (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150292-A1 | Soft Protease Inhibitors and Pro-Soft Forms Thereof | PREP, DPP4, PEPD | DPP4 2/4885FAP 51/4885DPP7 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.