Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870594 | 0.88 | NMT1 (0.71) | NMT1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL15028327 | 0.83 | NMT1 (0.80) | NMT1 | |
| SCHEMBL15028281 | 0.82 | NMT1 (0.75) | NMT1 | |
| SCHEMBL15028348 | 0.82 | NMT1 (0.70) | NMT1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL15028199 | 0.82 | NMT1 (0.69) | NMT1 | |
| SCHEMBL15028198 | 0.81 | NMT1 (0.82) | NMT1 | |
| SCHEMBL15028197 | 0.80 | NMT1 (0.67) | NMT1 | |
| SCHEMBL15013773 | 0.79 | NMT1 (0.66) | NMT1 | |
| SCHEMBL15028346 | 0.79 | NMT1 (0.79) | NMT1 | |
| SCHEMBL15028350 | 0.79 | NMT1 (1.00) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083991-A1 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL INNOVATIONS LIMITED (GB) | 2013-06-13 | — | — | WO | disclosed |