Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 0.60 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15705319 | 0.85 | HTT (0.68) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30133389 | 0.84 | HTT (0.71) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30277147 | 0.84 | HTT (0.71) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL24710086 | 0.84 | HTT (0.71) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29179558 | 0.84 | HTT (0.71) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5652155 | 0.82 | HTT (0.65) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29179603 | 0.82 | HTT (0.65) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL30852969 | 0.82 | HTT (0.65) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1568062 | 0.80 | KMT2A (0.71) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9011724 | 0.80 | HTT (0.75) | HTTALDH1A1TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014195400-A1 | KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-12-11 | — | — | WO | disclosed |
| WO-2013083206-A1 | DERIVATIVES OF 4-HYDROXY-1,2,3,4-TETRAHYDRONAPHTALEN-1-YL UREA AND THEIR USE IN THE TREATMENT OF, INTER ALIA, DISEASES OF THE RESPIRATORY TRACT | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-06-13 | — | — | WO | disclosed |