SCHEMBL1502910

SCHEMBL1502910

CC1(C)CC1(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24306251 0.82
SCHEMBL14175334 0.80
SCHEMBL4550217 0.80
SCHEMBL17863706 0.76
SCHEMBL25002994 0.74
SCHEMBL16934000 0.73
SCHEMBL1502907 0.73
SCHEMBL15351668 0.73
SCHEMBL8355299 0.73
SCHEMBL13236572 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2603079-B1 POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 MERCK SHARP & DOHME (US) 2018-09-19 EP claimed
EP-2721029-B1 IMIDAZOPYRIDIN-2-ONE DERIVATIVES MERCK SHARP & DOHME (US) 2018-07-18 EP claimed
US-9315518-B2 Imidazopyridin-2-one derivatives MERCK SHARP & DOHME CORP. (US) 2016-04-19 US claimed
US-20140350002-A1 IMIDAZOPYRIDIN-2-ONE DERIVATIVES MERCK SHARP & DOHME CORP. (US) 2014-11-27 US claimed
US-8765784-B2 Positive allosteric modulators of MGLUR2 MERCK SHARP & DOHME CORP. (US) 2014-07-01 US claimed
EP-2721029-A1 IMIDAZOPYRIDIN-2-ONE DERIVATIVES Merck Sharp & Dohme Corp. (US) 2014-04-23 EP claimed
US-20130210768-A1 POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 MERCK SHARP & DOHME LLC 2013-08-15 US claimed
US-20130143880-A1 POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 MERCK SHARP & DOHME LLC 2013-06-06 US claimed
EP-2579717-A2 POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 Merck Sharp & Dohme Corp. (US) 2013-04-17 EP claimed
WO-2012174199-A1 IMIDAZOPYRIDIN-2-ONE DERIVATIVES MERCK SHARP & DOHME CORP. (US) 2012-12-20 WO claimed
WO-2011156245-A2 POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 MERCK SHARP & DOHME CORP. (US) 2011-12-15 WO claimed
US-20240360157-A1 TYK2 INHIBITORS BIOGEN MA INC. 2024-10-31 US disclosed
WO-2024124002-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed
WO-2024123966-A1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS THIRD HARMONIC BIO, INC. (US) 2024-06-13 WO disclosed
WO-2024026481-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2011022473-A1 BIARYL COMPOUNDS AND METHODS OF USE THEREOF AMBIT BIOSCIENCES CORPORATION (US) 2011-02-24 WO disclosed
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
US-20070043011-A1 Substituted benzanilide compound and noxious organism controlling agent MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-02-22 US disclosed
EP-0351647-A2 2,2-Difluorocyclopropyl derivates BAYER AG (DE) 1990-01-24 EP disclosed
EP-0351646-A2 Hydroxyalkinyl-azolyl derivatives BAYER AG (DE) 1990-01-24 EP disclosed