Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890181 | 0.87 | GRM2 (0.77) | GRM2 | |
| SCHEMBL6892056 | 0.83 | GRM2 (0.71) | GRM2 | |
| SCHEMBL6892975 | 0.83 | GRM2 (0.70) | GRM2 | |
| SCHEMBL6891394 | 0.83 | GRM2 (0.70) | GRM2 | |
| SCHEMBL6890122 | 0.82 | GRM2 (0.69) | GRM2 | |
| SCHEMBL1503012 | 0.82 | GRM2 (0.76) | GRM2 | |
| SCHEMBL1503048 | 0.81 | GRM2 (0.68) | GRM2 | |
| SCHEMBL6893183 | 0.81 | GRM2 (0.67) | GRM2 | |
| SCHEMBL6893676 | 0.81 | GRM2 (0.67) | GRM2 | |
| SCHEMBL6891170 | 0.80 | GRM2 (0.67) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | claimed |
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | disclosed |