Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.50 |
| ▸ | FNTA | P49354 | 5/20 | 0.38 |
| ▸ | FNTB | P49356 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715332 | 0.78 | FNTA (0.42) | DPP4FNTAFNTBF10NAMPT | |
| SCHEMBL8719745 | 0.75 | FNTA (0.46) | DPP4FNTAFNTBF10NAMPT | |
| SCHEMBL10272672 | 0.75 | FNTA (0.46) | DPP4FNTAFNTBNAMPT | |
| SCHEMBL9072487 | 0.74 | DPP4 (0.40) | DPP4FNTAFNTBF10NAMPT | |
| SCHEMBL10223242 | 0.73 | DPP4 (0.45) | DPP4FNTAFNTBF10NAMPT | |
| SCHEMBL15029863 | 0.72 | DPP4 (0.40) | DPP4 | |
| SCHEMBL11716231 | 0.71 | DPP4 (0.42) | DPP4FNTAFNTBF10NAMPT | |
| SCHEMBL8295445 | 0.71 | DPP4 (0.70) | DPP4 | |
| SCHEMBL15029451 | 0.71 | DPP4 (0.39) | DPP4 | |
| SCHEMBL18711467 | 0.70 | DPP4 (0.41) | DPP4FNTAFNTBF10NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150364-A1 | HETEROCYCLIC COMPOUND | ASTELLAS PHARMA INC. (JP) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150364-A1 | HETEROCYCLIC COMPOUND | IL2, NFATC1, ICOS | DPP4 4111/4885FNTA 1648/4885FNTB 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.