Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 18/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16730441 | 1.00 | TSHR (0.47) | TSHRSLC5A2PTPN1SLC5A1 | |
| SCHEMBL1670119 | 1.00 | TSHR (0.47) | TSHRSLC5A2PTPN1SLC5A1 | |
| SCHEMBL10227570 | 1.00 | TSHR (0.47) | TSHRSLC5A2PTPN1SLC5A1 | |
| SCHEMBL18522188 | 1.00 | TSHR (0.47) | TSHRSLC5A2PTPN1SLC5A1 | |
| SCHEMBL1670118 | 1.00 | TSHR (0.47) | TSHRSLC5A2PTPN1SLC5A1 | |
| SCHEMBL10276121 | 1.00 | TSHR (0.47) | TSHRSLC5A2PTPN1SLC5A1 | |
| SCHEMBL18511212 | 0.94 | TSHR (0.40) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL15030914 | 0.86 | SLC5A2 (0.35) | TSHRSLC5A2SLC5A1 | |
| SCHEMBL16090889 | 0.86 | SLC5A2 (0.40) | SLC5A2SLC5A1 | |
| SCHEMBL16727621 | 0.86 | SLC5A2 (0.40) | SLC5A2SLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466114-B2 | Glycoside derivatives and uses thereof | NOVARTIS AG (CH) | 2013-06-18 | — | — | US | disclosed |