SCHEMBL15031002

SCHEMBL15031002

CCN1CC(NC(C)=O)[C@@H](O)[C@H](O)C1CO

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OGA O60502 4/20 0.68
GAA P10253 6/20 0.56
GBA2 Q9HCG7 9/20 0.40
UGCG Q16739 3/20 0.40
MGAM O43451 2/20 0.40
SI P14410 2/20 0.40
AGL P35573 2/20 0.40
GBA1 P04062 2/20 0.40
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21348881 0.88 OGA (0.60) OGAGAAGBA2UGCG
SCHEMBL18052427 0.88 OGA (0.77) OGAGAAGBA2UGCGMGAM
SCHEMBL13339127 0.86 OGA (0.62) OGAGAAGBA2UGCGMGAM
SCHEMBL15521184 0.85 OGA (0.92) OGAGAAGBA2UGCGMGAM
SCHEMBL18052434 0.81 OGA (0.64) OGAGAAGBA2UGCGMGAM
SCHEMBL16968363 0.81 OGA (0.76) OGAGAAGBA2UGCGMGAM
SCHEMBL13339129 0.81 OGA (0.58) OGAGAAMGAM
SCHEMBL15521182 0.81 OGA (0.58) OGAGAAMGAM
SCHEMBL2436582 0.81 OGA (1.00) OGAGAAGBA2UGCGMGAM
SCHEMBL2430935 0.81 OGA (1.00) OGAGAAGBA2UGCGMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8466291-B2 1,5-dideoxy-1,5-imino-D-glucitol compounds ACADEMIA SINICA (TW) 2013-06-18 US disclosed