Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245302 | 0.90 | JAK2 (0.84) | JAK3JAK2 | |
| SCHEMBL16245118 | 0.88 | JAK2 (1.00) | JAK3JAK2 | |
| SCHEMBL15032794 | 0.88 | JAK2 (1.00) | JAK3JAK2 | |
| SCHEMBL16245306 | 0.87 | JAK2 (0.81) | JAK3JAK2 | |
| SCHEMBL15032690 | 0.87 | JAK2 (1.00) | JAK3JAK2 | |
| SCHEMBL16245120 | 0.87 | JAK3 (0.81) | JAK3JAK2 | |
| SCHEMBL15032680 | 0.87 | JAK3 (1.00) | JAK3JAK2 | |
| SCHEMBL16245014 | 0.87 | JAK3 (0.79) | JAK3JAK2 | |
| SCHEMBL15032687 | 0.86 | JAK2 (0.79) | JAK3JAK2 | |
| SCHEMBL15032706 | 0.86 | JAK2 (0.80) | JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013085802-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-06-13 | — | — | WO | disclosed |