SCHEMBL15033264

SCHEMBL15033264

CC(=O)[C@H](CS)NCS

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12843359 0.83
SCHEMBL10309809 0.83
SCHEMBL17524675 0.83
SCHEMBL16360193 0.80
SCHEMBL23030320 0.79 KDM4E (0.38)
SCHEMBL19155459 0.79 KDM4E (0.42)
SCHEMBL13261389 0.79 KDM4E (0.42)
SCHEMBL17538803 0.79 KDM4E (0.50)
SCHEMBL18231569 0.78 KDM4E (0.41)
SCHEMBL17377986 0.78 KDM4E (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896715-B2 Method for analyzing formyl glycine residue JCR PHARMACEUTICALS CO., LTD. (JP) 2018-02-20 US disclosed
WO-2016178979-A1 COMPOSITIONS FOR COLON CLEANSING AND THE TREATMENT OF GASTROINTESTINAL DISORDERS IRONWOOD PHARMACEUTICALS, INC. (US) 2016-11-10 WO disclosed
US-20160303247-A1 Antibody-Drug Conjugates and Related Compounds, Compositions, and Methods IGENICA BIOTHERAPEUTICS, INC. (US) 2016-10-20 US disclosed
US-20150044715-A1 METHOD FOR ANALYZING FORMYL GLYCINE RESIDUE JCR PHARMACEUTICALS CO., LTD. (JP) 2015-02-12 US disclosed
EP-1850832-B1 ADJUVANTING MATERIAL LIPOTEK PTY LTD (AU) 2014-12-31 EP disclosed
US-20140363454-A1 Antibody-Drug Conjugates, Compositions and Methods of Use IGENICA BIOTHERAPEUTICS, INC. (US) 2014-12-11 US disclosed
WO-2014197871-A2 ANTIBODY-DRUG CONJUGATES, COMPOSITIONS AND METHODS OF USE IGENICA BIOTHERAPEUTICS, INC. (US) 2014-12-11 WO disclosed
EP-1984386-B1 Methods for the synthesis of two or more dicarba bridges in organic compounds SYNGENE LTD (AU) 2013-10-09 EP disclosed
US-20130224228-A1 Antibody-Drug Conjugates and Related Compounds, Compositions, and Methods IGENICA, INC. (US) 2013-08-29 US disclosed
WO-2013085925-A1 ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS IGENICA, INC. (US) 2013-06-13 WO disclosed
WO-2007093013-A1 METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN ORGANIC COMPOUNDS MONASH UNIVERSITY (AU) 2007-08-23 WO disclosed