Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.65 |
| ▸ | CA1 | P00915 | 8/20 | 0.65 |
| ▸ | CA2 | P00918 | 8/20 | 0.65 |
| ▸ | CA9 | Q16790 | 8/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21011827 | 1.00 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL21011843 | 1.00 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL19257250 | 1.00 | CA12 (0.65) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL22290084 | 0.87 | TDP1 (0.67) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL26490214 | 0.85 | CA12 (0.78) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL10062839 | 0.85 | CA12 (0.78) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL4315244 | 0.85 | CA12 (0.78) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL24500735 | 0.85 | TDP1 (0.69) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13714460 | 0.85 | TDP1 (0.69) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL14028793 | 0.84 | TDP1 (0.62) | CA12CA1CA2CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9733240-B2 | General strategy for antibody library screening | MERCK PATENTS GMBH (DE) | 2017-08-15 | — | — | US | disclosed |
| US-20140357514-A1 | GENERAL STRATEGY FOR ANTIBODY LIBRARY SCREENING | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| WO-2013087215-A1 | GENERAL STRATEGY FOR ANTIBODY LIBRARY SCREENING | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |