Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4549272 | 0.87 | KCNH2 (1.00) | KCNH2KCNJ1 | |
| SCHEMBL15036947 | 0.81 | KCNJ1 (0.64) | KCNH2KCNJ1 | |
| SCHEMBL10233973 | 0.79 | KCNH2 (0.82) | KCNH2KCNJ1 | |
| SCHEMBL16227952 | 0.79 | KCNJ1 (1.00) | KCNH2KCNJ1 | |
| SCHEMBL16227351 | 0.79 | KCNJ1 (1.00) | KCNH2KCNJ1 | |
| SCHEMBL16227783 | 0.79 | KCNJ1 (1.00) | KCNH2KCNJ1 | |
| SCHEMBL15036771 | 0.79 | KCNJ1 (1.00) | KCNH2KCNJ1 | |
| SCHEMBL15036945 | 0.78 | KCNJ1 (1.00) | KCNH2KCNJ1 | |
| SCHEMBL15196874 | 0.78 | KCNH2 (0.79) | KCNH2KCNJ1 | |
| SCHEMBL4549341 | 0.77 | KCNH2 (1.00) | KCNH2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090271-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2013-06-20 | — | — | WO | disclosed |